By T.V. Chirila (Eds.)
With an more and more elderly inhabitants, eye ailments have gotten extra frequent. Biomaterials have contributed in recent times to varied scientific units for the recovery of eyesight, enhancing many sufferers' caliber of existence. for that reason, biomaterials and regenerative drugs have gotten more and more vital to the advances of ophthalmology and optometry. Biomaterials and regenerative drugs in ophthalmology studies the current prestige and destiny path of biomaterials and regenerative medication during this vital field.
Part one discusses purposes within the anterior section of the attention with chapters on such issues as advances in intraocular lenses (IOLs), artificial corneal implants, touch lenses, and tissue engineering of the lens. half then reports functions within the posterior phase of the attention with such chapters on designing hydrogels as vitreous substitutes, retinal fix and regeneration and the advance of tissue engineered membranes. Chapters partially 3 talk about different pertinent issues similar to hydrogel sealants for wound fix in ophthalmic surgical procedure, orbital enucleation implants and polymeric fabrics for orbital reconstruction.
With its uncommon editor and foreign crew of members, Biomaterials and regenerative drugs in ophthalmology is a regular reference for scientists and clinicians, in addition to all these interested by this ophthalmology.
- Reviews the more and more vital function of biomaterials and regenerative medication within the development of ophthalmology and optometry
- Provides an outline of the current prestige and destiny path of biomaterials and regenerative medication during this vital field
- Discusses functions in either the anterior and prosterior segments of the attention with chapters on such subject matters as man made corneal implants and retinal fix and regeneration
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Extra resources for Biomaterials and Regenerative Medicine in Ophthalmology
2008). , 2004). , 2006). Surface modification of IOL materials has also been investigated as a way of controlling LEC growth and adhesion to inhibit PCO development. , 2003). , 2002). Yuen et al. , 2006). , 1991). , 2006). , 2006). An alternative approach for reducing PCO is the complete prevention of protein and subsequent cell adhesion to the IOL surface. , 2007). , 2006). , 2005). 5 Drug-releasing IOLs for mitigating complications IOLs that deliver drugs that hinder LEC proliferation or reduce inflammation may have potential for reducing complications.
Resnikoff S, Pascolini D, Etya’ale D, Kocur I, Pararajasegaram R, Pokharel G P, Mariotti S P (2004), ‘Global data on visual impairment in the year 2002’, Bull World Health Organ, 82, 844–851. Advances in intraocular lens development 33 Rowe N A, Biswas S, Lloyd I C (2004), ‘Primary IOL implantation in children: a risk analysis of foldable acrylic v PMMA lenses’, Br J Ophthalmol, 88, 481–485. Schroeder A C, Schmidbauer J M, Sobke A, Seitz B, Ruprecht K W, Herrmann M (2008), ‘Influence of fibronectin on the adherence of Staphylococcus epidermidis to coated and uncoated intraocular lenses’, J Cataract Refract Surg, 34, 497–504.
The B3 human lens epithelial cells were grown in modified Eagle’s medium (MEM) F15 media, with 20% fetal bouine serum (FBS), and with 200 mM aphidicolin (a mitosis inhibitor, used to determine effects of drugs solely on migration). Photographs were taken immediately after scraping cells off one side of the dish (panels (a), (b), (c), and 3 days later (panels (d), (e) and (f). Panels (a) and (d) are untreated controls. Panels (b) and (e) are cells treated with GM6001. 001) reduction in migration when compared with untreated control.