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By Z. M. Bacq and Peter Alexander (Eds.)

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2-2) some of the radicals then react with one another and not with the dissolved material, and the specific inactivation dose rises. This effect has been studied in great detail for another enzyme and the changeover from the case where almost all ζν> Ο, \ ^> ^ \ 0 " Q ^Jtr— ^<£> ^ Specific inactivation dose ΰ/θχ70' 7 4 70~* 70' 5 70'•* Concentration 70 -3 1070~ of enzyme (θ) FIG. 2-2. The relationship between the concentration ( C ) of carboxypeptidase in aqueous solution (expressed as g of enzyme/ g of enzyme + water) and the dose of x-rays ( D ) required to reduce the activity of the solution to 37 per cent of its original value.

O. and L A W R E N C E , J. CORMACK, A. 1952, 25. , Am. J. Roentgenol, 1 R. , Symposium on Radiobiology, p. 9 7 , John Wiley, New York, 1952. 26. GRAY, L. , Actions chimiques et biologiques des Radiation, vol. 1. p. 4 . publ. Masson 1955 27. , 4, 479 HIRSCHFELDER, J. O. and TAYLOR, H. , J. Chem. , 1936, 44 28. 29. FUNDAMENTALS F R A N C K , J. y 33. RADIOBIOLOGY S. C. and L I V I N G S T O N , R . , / . Am. Chem. Soc, 1936, 5 8 , 612 and L I V I N G S T O N , R . , Rev. Mod. , 1949, 2 1 , 505 F O R S T E R , T .

The half-life of an isotope is the period in which its activity falls to one half. Since the range of /-radiations is so very much greater it is necessary to treat these differently from β-rays, and the Κ constants calculated by M A Y N E O R D are generally used. This important field of calibrating radioactive isotopes is dealt with in a number of reviews ( M A Y N E O R D and 10 10 6 3 9 SINCLAIR ). 10 M E A S U R E M E N T OF D O S E If the dose is expressed in roentgens the basic measurement is the determination of the number of ion pairs formed in a volume of gas.

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