By Paul A. Iaizzo
This booklet covers the most recent details at the anatomic positive aspects, underlying physiologic mechanisms, and coverings for illnesses of the center. Key chapters handle animal types for cardiac learn, cardiac mapping platforms, heart-valve affliction and genomics-based instruments and know-how. once more, a better half of supplementary movies provide specific insights into the operating middle that increase the certainty of key issues in the textual content. complete and state-of-the artwork, the guide of Cardiac Anatomy, body structure and units, 3rd version presents clinicians and biomedical engineers alike with the authoritative details and historical past they should paintings on and enforce tomorrow’s new release of life-saving cardiac devices.
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Additional resources for Handbook of Cardiac Anatomy, Physiology, and Devices
Embryonic origins of cardiogenic mesoderm. Dev Dyn 223:307–320 25. Garcia-Martinez V, Schoenwolf GC (1993) Primitive-streak origin of the cardiovascular system in avian embryos. Dev Biol 159:706–719 26. Psychoyos D, Stern CD (1996) Fates and migratory routes of primitive streak cells in the chick embryo. Development 122:1523–1534 27. DeHaan RL (1963) Organization of the cardiogenic plate in the early chick embryo. Acta Embryol Moprhol Exp 6:26–38 28. Ehrman LA, Yutzey KE (1999) Lack of regulation in the heart forming region of avian embryos.
In ribs 1–10, the head is connected to the shaft by a narrowing called the neck. At the junction of the head and the neck is a tubercle that has an articular surface for articulation with the costal facet of the transverse process. Ribs 11 and 12 do not articulate with the transverse process of their respective vertebra and do not have a tubercle or, therefore, a deﬁned neck portion. The sternum is the ﬂat bone making up the median anterior part of the thoracic cage (Fig. 2). It is composed of three parts—the manubrium, body, and xiphoid process.
2 Cross-sectional view of human heart tube fusion. (A) Day 20, cephalocaudal and lateral folding brings bilateral endocardial tubes into the ventral midline of the embryo. (B) Day 21, start of heart tube fusion. (C) Day 22, complete fusion, resulting in the beating primitive heart tube. Color code of the embryonic primary germ layer origin: blue/ purple = ectoderm; red = mesoderm; orange = endoderm; yellow = second heart ﬁeld. FHF ﬁrst heart ﬁeld, SHF second heart ﬁeld cavity [18, 30]. During the fusion of the endocardial tubes, the myocardium secretes an extracellular (acellular) matrix (enriched in chondroitin sulfate, versican, heparan sulfate, hyaluronic acid, hyaluronan, and proteoglycans), forming the cardiac jelly layer separating the myocardium and endocardium .