By Evangeline B. Handog, Maria Juliet Enriquez-Macarayo
This ebook sheds new mild on pigmentary problems in individuals with brown dermis. Brown pores and skin encompasses many races and ethnicities. because of migration, individuals with brown epidermis are obvious nearly all around the global.
A wide selection of pigmentary problems exists between this inhabitants however the most annoying and hard are melasma and vitiligo
This publication covers those issues, between humans of brown epidermis, from the epidemiology to administration, in an in depth but easy-to-read and easy-to-use style.
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Extra info for Melasma and Vitiligo in Brown Skin
Histochemical and immunohistochemical study in melasma: evidence of damage in the basal membrane. Am J Dermatopathol. 2011;33:291–5. 37. Morphologic changes and the expression of alpha-melanocyte stimulating hormone and melanocortin-1 receptor in melasma lesions: a comparative study. Am J Dermatopathol. 2010;32:676–82. Clues to the pathogenesis of melasma from its histologic findings. Pigmentary Disorders. 2014;1:141. 4 Pathogenesis of Melasma 31 39. Melasma: a clinical, light microscopic, ultrastructural, and immunofluorescence study.
4. Melasma induced by oral contraceptive drugs. JAMA. 1967;199:601–5. 5. The dermal stem cell factor and c-kit are overexpressed in melasma. Br J Dermatol. 2006;154:1094–9. Pendulous melanocytes: a characteristic feature of melasma and how it may occur. Br J Dermatol. 2012;166:684–6. Mechanisms of melanogenesis inhibition by 2,5-dimethyl-4-hydroxy-3(2H)-furanone. Br J Dermatol. 2007;157:242–8. 8. Ethnic considerations in the treatment of Hispanic and Latin- American patients with hyperpigmentation.
In vivo reflectance confocal microscopy for skin imaging in melasma. J Nippon Med Sch. 2013;80(3):172–3. 1 Histopathology of Melasma Racial variations exist in terms of epidermal melanin content and melanosome distribution in pigmented skin compared with fair-skinned individuals . Melanosomes in darker skin types are distributed throughout the entire epidermis with dense clusters in the basal layer [2–4]. In contradistinction, fewer melanosomes in the basal cell layer are observed in fair-skinned individuals [5, 6].