By Charcosset, Catherine (Auth.)
Membrane methods are more and more utilized in pharmaceutical and biochemical engineering and biotechnology for focus and purification, synthesis of molecules and drug supply platforms, and help for biochemical reactions. This publication presents a state-of-the artwork assessment of the classical membrane tactics utilized in pharmaceutical and biochemical engineering and biotechnology, corresponding to ultrafiltration, microfiltration, virus filtration, membrane chromatography, membrane emulsification, liquid membranes and membrane bioreactors. It describes the final principles (principles, number of configurations, membranes, parameters, etc.), contemporary advancements (fouling keep an eye on, bring up permeate flux and selectivity, etc.), functions, and theoretical descriptions. additional, it offers rising tactics similar to solvent resistant nanofiltration and membrane crystallization.
- Presents classical membrane procedures similar to ultrafiltration, microfiltration, virus filtration, membrane chromatography, membrane emulsification, liquid membranes and membrane bioreactors
- Presents rising tactics comparable to solvent resistant nanofiltration and membrane crystallization
- Gives an entire description of every strategy (principles, membrane fabrics and units, fouling keep an eye on, and theoretical description)
- Contains a number of examples of applications
- Includes a uniform notation in the course of the e-book improving the presentation and figuring out of the content
- Includes wide record of references
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Additional resources for Membrane Processes in Biotechnologies and Pharmaceutics
Backflushing is very effective at removing particle cakes from the membrane surface. It can also remove foulants from the membrane pores when a chemical cleaning solution is used. Rapid backpulsing, which involves reversing the TMP for a fraction of a second once every few seconds, has been investigated for various foulants, with up to 30-fold improvements in flux [68–70]. For example, Mores and Davis  investigated yeast cells deposited on CA membranes during cross-flow MF. The membranes were then cleaned using individual backpulses at varying backpulse durations, TMPs and shear rates.
B. Petrus, H. Li, V. Chen, N. Norazman, Enzymatic cleaning of ultrafiltration membranes fouled by protein mixture solutions, J. Membr. Sci. 325 (2008) 783–792. Principles on membrane and membrane processes 41  H. Lee, G. Amy, J. Cho, Y. -H. S. Kim, Cleaning strategies for flux recovery of an ultrafiltration membrane fouled by natural organic matter, Water Res. 35 (2001) 3301–3308.  G. Tra¨ga˚rdh, Membrane cleaning, Desalination 71 (1989) 325–335.  P. F. Migdal, T. Be´ne´zech, Chemical cleaning of a tubular ceramic microfiltration membrane fouled with a whey protein concentrate suspension – characterization of hydraulic and chemical cleanliness, J.
Wiesner, A comparison of vertical scanning interferometry (VSI) and atomic force microscopy (AFM) for characterizing membrane surface topography, pp. 410–417, Copyright Elsevier (2006). used to provide a 3D representation of MF membranes . CSLM has also been applied for visualizing protein adsorption to ion-exchange membranes  and characterization of membrane fouling during filtration . 1 mm. CSLM is therefore only applicable to MF membranes. 13 Confocal CSLM image of the Immunodyne membrane mounted in immersion oil.