By Ruhong Zhou
This publication offers a finished evaluation of the basics of nanotoxicity modeling and its implications for the improvement of novel nanomedicines. It lays out the basics of nanotoxicity modeling for an array of nanomaterial platforms, starting from carbon-based nanoparticles to noble metals, steel oxides, and quantum dots. the writer illustrates how molecular (classical mechanics) and atomic (quantum mechanics) modeling techniques could be utilized to strengthen our figuring out of many very important features of this serious nanotoxicity factor. every one bankruptcy is geared up by means of different types of nanomaterials for practicality, making this an incredible booklet for senior undergraduate scholars, graduate scholars, and researchers in nanotechnology, chemistry, physics, molecular biology, and computing device technological know-how. it's also of curiosity to educational and execs who paintings on nanodrug supply and similar biomedical functions, and aids readers of their biocompatibility evaluate efforts within the coming age of nanotechnology. This ebook additionally presents a severe evaluate of complicated molecular modeling and different computational concepts to nanosafety, and highlights present and destiny biomedical functions of nanoparticles when it comes to nanosafety.
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Extra resources for Modeling of Nanotoxicity: Molecular Interactions of Nanomaterials with Bionanomachines
Nat Nano 3 (4):191–192 18. Nel A, Xia T, Mädler L, Li N (2006) Toxic potential of materials at the nanolevel. Science 311(5761):622–627 19. Ge C, Du J, Zhao L, Wang L, Liu Y et al (2011) Binding of blood proteins to carbon nanotubes reduces cytotoxicity. Proc Natl Acad Sci USA 108(41):16968–16973 20. Kang SG, Zhou G, Yang P, Liu Y, Sun B et al (2012) Molecular mechanism of pancreatic tumor metastasis inhibition by gd@c82(oh)22 and its implication for de novo design of nanomedicine. Proc Natl Acad Sci USA 109(38):15431–15436 21.
Chem Res Toxicol 25(1):15–34 15. Geim AK (2009) Graphene: status and prospects. Science 324(5934):1530–1534 16. Nel AE, Madler L, Velegol D, Xia T, Hoek EMV et al (2009) Understanding biophysicochemical interactions at the nano-bio interface. Nat Mater 8(7):543–557 17. Zhao Y, Xing G, Chai Z (2008) Nanotoxicology: are carbon nanotubes safe? Nat Nano 3 (4):191–192 18. Nel A, Xia T, Mädler L, Li N (2006) Toxic potential of materials at the nanolevel. Science 311(5761):622–627 19. Ge C, Du J, Zhao L, Wang L, Liu Y et al (2011) Binding of blood proteins to carbon nanotubes reduces cytotoxicity.
Yang ZX, Kang SG, Zhou RH (2014) Nanomedicine: De novo design of nanodrugs. Nanoscale 6(2):663–677 13. Feng LZ, Liu ZA (2011) Graphene in biomedicine: opportunities and challenges. Nanomedicine 6(2):317–324 14. Sanchez VC, Jachak A, Hurt RH, Kane AB (2012) Biological interactions of graphene-family nanomaterials: an interdisciplinary review. Chem Res Toxicol 25(1):15–34 15. Geim AK (2009) Graphene: status and prospects. Science 324(5934):1530–1534 16. Nel AE, Madler L, Velegol D, Xia T, Hoek EMV et al (2009) Understanding biophysicochemical interactions at the nano-bio interface.