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Extra info for MR Imaging and Spectroscopy of Central Nervous System Infection
Sinha et al. , the free induction decay) that lasts for a long time. , in the MR image), this manifests itself as a sharp spectral line, and represents the bulk of the signal detected by a typical MR scanner. In contrast, the other “pool” consists of protons that are “bound” to large macromolecules such as proteins and membrane and results in heavily restricted motion of these protons. The restricted motion in turn enhances the static or slowly varying (low frequency) components of the magnetic field fluctuations, which are the time-dependent perturbations responsible for T2-relaxation.
The mean square distance,
Courtesy Drs. ) column shows the images of the two slices acquired at b = 1000 s/mm2. Several points are to be noted. One can immediately observe the bright zone compromised by a cerebral stroke in the left image. A hyperintense zone indicates a region where the protons are diffusing less than in the zones with lower intensity. A smaller value of diffusion coefficient (as in the stroke region) causes lesser dephasing of the spins and consequently more MR signal than that arising from normal tissue zones where the protons are able to diffuse to a greater extent.