Download Phosphorus Chemistry I: Asymmetric Synthesis and Bioactive by Jean-Luc Montchamp PDF

By Jean-Luc Montchamp

Each overview in the quantity seriously surveys one point of that subject and areas it in the context of the amount as a complete. the main major advancements of the final five to ten years are awarded utilizing chosen examples to demonstrate the rules mentioned. The assurance isn't really meant to be an exhaustive precis of the sector or contain huge amounts of information, yet may still otherwise be conceptual, targeting the methodological pondering that might permit the non-specialist reader to appreciate the data provided. Contributions additionally provide an outlook on power destiny advancements within the field.

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Extra resources for Phosphorus Chemistry I: Asymmetric Synthesis and Bioactive Compounds

Example text

1 Inhibitors of Folylpoly-γ-Glutamyl Synthetase . . . . . . . . . . . . . . . . . . . 2 Inhibitors of Aspartate Transcarbamoylase . . . . . . . . . . . . . . . . . . . . . 3 Inhibitors of Tubulin Polyglutamylation . . . . . . . . . . . . . . . . . . . . . . . 4 Antiproliferative Phosphinates . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5 Phosphinates as Sugar Mimetics .

6 Phosphinic Acids as Antibiotics or for Parasitic Diseases . . . . . . . . . . . . . . . . . 1 Phosphonophosphinic Acid: Quinolone Prodrugs . . . . . . . . . . . . . . . . . . 2 Strained Cyclic Phosphinic Acids, Inhibitors of Glutamate Racemase (GR) . . . . 3 Cyclobutyl-1,3-Thiazolyl Phosphinic Acids . . . . . . . . . . . . . . . . . . . . . 4 Antimalarial Phosphinates: Inhibitors of Dihydrofolate Synthase .

6 Phospholipases Inhibitors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6 Phosphinic Acids as Antibiotics or for Parasitic Diseases . . . . . . . . . . . . . . . . . 1 Phosphonophosphinic Acid: Quinolone Prodrugs . . . . . . . . . . . . . . . . . . 2 Strained Cyclic Phosphinic Acids, Inhibitors of Glutamate Racemase (GR) . . . . 3 Cyclobutyl-1,3-Thiazolyl Phosphinic Acids .

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