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By Lehninger A., Nelson D.L., Cox M.M.

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Rnersare called oligomers (Greek oligos, "few"). Synthesisof macromolecules is a major energy-consumingactivity of cells. Interactionsbetweenbiomoleculesare invariably stereospecific, requiring speci-flcconfigurationsin the interactingmolecules. Figure 1-17 shows three ways to illustrate the stereochemistry,or configuration,of simple molecules. The perspectivediagram speciflesstereochemistryunambiguously,but bond anglesand center-to-centerbond lengths are better representedwith ball-and-stickmodels.

Thetreein Figure3-33 is a "consensus"tree,which usesseveralcomparisons suchastheseto makethe of evolutionaryrelatedness of a groupof organisms. bestestimates by 02 diffusinginto the cell. With increasingcell size, however,surface-to-volume ratio decreases,until metabolism consumes02 faster than diffusion can supply it. Metabolismthat requires02 thus becomesimpossible as cell sizeincreasesbeyonda certain point, placinga theoreticalupper limit on the sizeof cells. a commonprogenitor(Fig. 1-4). TWolarge groupsof single-celledmicroorganismscan be distinguishedon genetic and biochemical grounds: Bacteria and Archaea.

Ellu}ar ftimensions Are[innited byDlffusion Cytoplasm Aqueous cell contents and suspendedparticles and organelles. ; I centrifugeat 150,0009 | V Pellet: particles and organelles Ribosomes,storage granules, mitochondria, chloroplasts, lysosomes, endoplasmic reticulum. FI6URE 1 - 3 The universalfeaturesof living cells,All cellshavea nucleusor nucleoid,a plasmamembrane, and cytoplasm. l the resultingextractat 150,000g for hour. Most cellsare microscopic,invisibleto the unaidedeye. What limits the dimensions of a cell?

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