Download Salivary Gland Development and Regeneration: Advances in by Seunghee Cha PDF

By Seunghee Cha

This ebook presents a accomplished replace at the most modern details and information which emerged from translational and simple technological know-how learn endeavors, focusing on the regeneration of salivary glands. The assurance contains salivary gland development and improvement, stem telephone remedy, bioengineering of salivary glands, and views on and useful techniques to recovery of secretory functionality. extra in particular, one of the person themes addressed are many of the sorts of stem cellphone of worth for cellphone substitute remedy, technological advances with admire to 3D printing, gene remedy, organ tradition of salivary glands, and surgical facets of the feasibility and practicality of transplantation. Readers will locate important functional counsel on sensible restorations of broken salivary glands and stimulating insights into capability destiny instructions in salivary gland regeneration learn. The authors are all said specialists from a variety of educational and scientific backgrounds. therefore, the publication could be of curiosity not just to clinicians, reminiscent of normal dental practitioners, oral medication experts, and surgeons who deal with dry mouth sufferers, but additionally to biomedical engineers, stem mobile researchers, and transplant surgeons.

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Salivary Gland Development and Regeneration: Advances in Research and Clinical Approaches to Functional Restoration

This e-book presents a entire replace at the most modern info and information which emerged from translational and simple technological know-how study endeavors, concentrating on the regeneration of salivary glands. The insurance comprises salivary gland development and improvement, stem telephone remedy, bioengineering of salivary glands, and views on and useful ways to recovery of secretory functionality.

Extra info for Salivary Gland Development and Regeneration: Advances in Research and Clinical Approaches to Functional Restoration

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5 Hierarchical clustering of differentially expressed mRNAs in “Maintenance of Cell Number” GO category. The top 10 % of differentially expressed genes were selected from the “Maintenance of Cell Number” category (GO:0098727), a subcategory of “Developmental Process” category (GO:0032502), one of the most conserved categories (Fig.  The hierarchical clustering provided two distinct groups including a preferentially upregulated gene group and a downregulated gene group, suggesting that differentially expressed genes between in vivo and ex vivo are relatively well conserved.

Wendy Knosp and Dr. Matthew Hoffman (National Institute for Dental and Craniofacial Research, NIH, DHHS, USA) for critical proofreading. References 1.  Nanoparticle-mediated gene silencing confers radioprotection to salivary glands in vivo. Mol Ther. 2013;21(6):1182–94. 42.  Pericytes: developmental, physiological, and pathological perspectives, problems, and promises. Dev Cell. 2011;21(2):193– 215. 001. Arnold K, Sarkar A, Yram MA, Polo JM, Bronson R, Sengupta S, Seandel M, Geijsen N, Hochedlinger K.

2013;9(3):199–205. 25224. Fruhbeis C, Frohlich D, Kuo WP, Amphornrat J, Thilemann S, Saab AS, Kirchhoff F, Mobius W, Goebbels S, Nave KA, Schneider A, Simons M, Klugmann M, Trotter J, Kramer-Albers EM. Neurotransmitter-triggered transfer of exosomes mediates oligodendrocyte-neuron communication. PLoS Biol. 2013;11(7):e1001604. 1001604.  DLK1 regulates branching morphogenesis and parasympathetic innervation of salivary glands through inhibition of NOTCH signalling. Biol Cell. 2014;106(8):237–53.

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