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By Friedrich Spener, Manju Mukherjea (auth.), H. J. Hilderson (eds.)

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The reader is referred to these reviews for further detailed information. 2. PHOSPHOLIPID TRANSFER PROTEINS So far, fluorescent phospholipids have been used to study the structure and function of three mammalian phospholipid transfer proteins. These proteins are Fluorescent Phospholipids: Studies on Transfer Proteins 23 (i) the phosphatidylcholine transfer protein (PC-TP), which is specific for PC; (ii) the phosphatidylinositol transfer protein (PI-TP), which shows marked preference for PI but is also able to transfer PC and, to a lesser extent, phosphatidylglycerol (PG); and (iii) the nonspecific lipid transfer protein (nsL-TP), which transfers most phospholipids, as well as glycolipids and cholesterol, and is now known to be identical to sterol carrier protein 2 (Trzaskos and Gaylor, 1983).

1987, Purification and properties of two phospholipid transfer proteins from yeast, Biochem. Cell Bioi. 65:195-202. , Gotto, A. , and Smith, L. , 1985, Human liver fatty acid binding protein eDNA and amino acid sequence, J. Bioi. Chem. 260:2629-2632. , Noland, B. , Scallen, T. , and Vahouny, G. , 1982, Sterol carrier protein 2, delivery of cholesterol from adrenal lipid droplets to mitrochondria for pregnenolone synthesis, J. Bioi. Chem. 257:8928-8934. , 1982, The presence of phospholipid transfer proteins in filamentous fungi, in Biochemistry and Metabolism of Plant Lipids (J.

Chern. 263:14189-14195. , 1986, Purification and characterization of a non-specific lipid transfer protein from geminated castor bean endosperms which transfer phospholipids and galactolipids, Biochim. Biophys. Acta 876:116-123. Wetterau, J. , and Zilversmit, D. , 1984, Quantitation of lipid transfer activity, Methods Biochem. Anal. 30:119-226. Wetterau, J. , and Zilversmit, D. , 1986, Localization of intracellular triacylglycerol and cholesteryl ester transfer activity in rat tissues, Biochim.

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