By Somesh Gupta, Mats J. Olsson, Amrinder J. Kanwar, Jean-Paul Ortonne
Even supposing vitiligo has commonly been very tough to regard, a brand new leap forward surgical procedure is increasing thoughts for practitioners and patients.Standard remedies depend upon the severity of the situation and the patient's emotions of disfigurement. Cover-up cosmetics paintings good for a few humans. different extra refined kinds of therapy comprise progressively constructing colour again within the depigmented parts (repigmentation) by means of PUVA or different ultraviolet gentle remedies, yet this can be super gradual and in depth, frequently requiring numerous hundred treatments.This new type of remedy, which includes surgically transplanting melanocytes into the white components, is such a lot profitable in sufferers with sturdy vitiligo over lower than 30% in their physique floor quarter. It enhances clinical cures achieve whole and sustained repigmentation and is quickly rising in popularity in all significant centers.This is the 1st publication on hand which describes this significant strengthen in detail.Explains the recent remedy of surgically transplanting melanocytes into the affected parts of the surface to supply dermatologists and surgeons with the most recent cutting-edge informationWritten via the overseas leaders who pioneered this treatmentPresents all of the most recent info at the subject, casting off the necessity to seek via a number of resources for particular info
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Additional resources for Surgical Management of Vitiligo
Br J Dermatol 2004;150:435–43. 5 Nordlund JJ, Ortonne JP. Vitiligo vulgaris. ) The Pigmentary System: Physiology and Pathophysiology. New York: Oxford University Press, 1998;513–51. 6 Ortonne JP, Schmitt D, Thivolet J. PUVA-induced repigmentation of vitiligo: scanning electron microscopy of hair follicles. J Invest Dermatol 1980;74:40–2. 7 Cui J, Shen LY, Wang GC. Role of hair follicles in the repigmentation of vitiligo. J Invest Dermatol 1991;97: 410–16. 8 Horikawa T, Norris DA, Yohn JJ, et al.
32 Bolognia JL, Orlow SJ, Glick SA. Lines of Blaschko. J Am Acad Dermatol 1994;31:157–90. 33 Hann SK, Chang JH, Lee HS, Kim SM. The classification of segmental vitiligo on the face. Yonsei Med J 2000;41:209–12. CHAPTER 4 Medical treatment of vitiligo Thierry Passeron and Jean-Paul Ortonne Individuals affected by vitiligo have a vast reduction of quality of life. The color contrast between healthy pigmented skin and the depigmented vitiligo patches can give patients psychological problems [1,2].
6 Ortonne JP, Schmitt D, Thivolet J. PUVA-induced repigmentation of vitiligo: scanning electron microscopy of hair follicles. J Invest Dermatol 1980;74:40–2. 7 Cui J, Shen LY, Wang GC. Role of hair follicles in the repigmentation of vitiligo. J Invest Dermatol 1991;97: 410–16. 8 Horikawa T, Norris DA, Yohn JJ, et al. Melanocyte mitogens induce both melanocyte chemokinesis and chemotaxis. J Invest Dermatol 1995;104:256–9. 9 Lei TC, Vieira DW, Hearing VJ. In vitro migration of melanoblasts require matrix metalloproteinase-2: implication to vitiligo therapy by photochemotherapy.