Download The Duration and Safety of Osteoporosis Treatment: Anabolic by Stuart Silverman, Bo Abrahamsen PDF

By Stuart Silverman, Bo Abrahamsen

Providing a complete assessment of short-and long term opposed occasions of either antiresorptive and anabolic medicines, this useful advisor updates the clinician at the pathophysiology of osteoporosis and the rules in the back of our current and destiny prescribed drugs. top practitioners within the box research all present literature and information in regards to the length and defense of those treatments, with suggestions for clinicians on decision-making and most sensible practices for osteoporosis sufferers. an outline of the pathophysiology and epidemiology of osteoporosis and dialogue of either anabolic and antiresorptive medicines is by means of fracture hazard evaluation and an exam of remedy mess ups. subsequent, a few chapters are devoted to the prognosis, presentation and administration of ordinary femur fractures and osteonecrosis of the jaw (ONJ), each one of that are major sufferer issues while utilizing those osteoporosis remedies. The creation and usage of drug vacations is usually mentioned, in addition to the long term outlook for administration of osteoporotic sufferers. Written and edited through specialists within the box, The period and defense of Osteoporosis Treatment is a balanced source for researchers, practitioners and policy-makers alike for medical decision-making and sufferer care.

Show description

Read or Download The Duration and Safety of Osteoporosis Treatment: Anabolic and Antiresorptive Therapy PDF

Best orthopedics books

Cancer in the Spine: Comprehensive Care

Extraordinary physicians and researchers from prestigious melanoma facilities around the globe provide their services in present and cutting edge administration of melanoma within the backbone. those authors compile the newest considering from varied fields of drugs to supply, in a single quantity, a advisor to coordinated administration of all facets of spinal tumors overlaying chemo- and radiation treatment, discomfort administration, diagnostic radiology, in addition to reconstructive surgical procedure and palliative care.

Classification and diagnosis in orthopaedic trauma

A hugely illustrated booklet offering concise but complete info on fracture category and administration. The textual content has been built in response to the necessities of orthopaedic surgeons in education. the 1st part covers normal ideas comparable to terminology and working with a number of trauma; following sections take the reader systematically via areas of the physique and a number of the attainable fractures, overlaying prognosis, remedy and therapeutic in each one case.

Atlas of Human Limb Joints

The purpose of this e-book is to give as thoroughly as attainable an outline of the joints of the human limbs, utilizing images and drawings of anatomical dissections. latest descriptive anatomical money owed are frequently theoretical and never associated with practical job of the joints involved; they lack sensible demonstra­ tion of the anatomy.

Advances in Metallic Biomaterials: Tissues, Materials and Biological Reactions

This e-book studies primary advances within the use of metal biomaterials to reconstruct tough tissues and blood vessels. It additionally covers the newest advances in consultant metal biomaterials, corresponding to stainless steels, Co-Cr alloys, titanium and its alloys, zirconium, tantalum and niobium dependent alloys.

Extra resources for The Duration and Safety of Osteoporosis Treatment: Anabolic and Antiresorptive Therapy

Sample text

Denosumab may also have a greater impact on protecting cortical bone than bisphosphonates, which is likely to contribute to its efficacy in reducing fractures. However, the effects of denosumab rapidly reverse when treatment stops which means that ensuring compliance is even more important if potential benefits are to be sustained. Another difference is the potential use of denosumab in patients with impaired renal function, in whom use of bisphosphonates is contraindicated. Estrogens: Background and Current Status The recognition that the decline in estrogen production at the menopause was associated with bone loss dates back to the time of Albright more than half a century ago.

Trends in hip fracture incidence and in the prescription of antiosteoporosis medications during the same time period in Belgium (2000–2007). Arthritis Care Res. J. Moon et al. 2012;64(5):744–50. 21607 [published Online First: Epub Date]. 88. Alves SM, Economou T, Oliveira C, et al. Osteoporotic hip fractures: bisphosphonates sales and observed turning point in trend. A population-based retrospective study. Bone. 2013;53(2):430–6. 1016/j. 014 [published Online First: Epub Date]. 89. Abrahamsen B, Vestergaard P.

There are several respects in which the differences between bisphosphonates and denosumab have practical consequences. It appears that the effects of denosumab to increase BMD continue on prolonged treatment, whereas they may plateau earlier on bisphosphonates. Denosumab may also have a greater impact on protecting cortical bone than bisphosphonates, which is likely to contribute to its efficacy in reducing fractures. However, the effects of denosumab rapidly reverse when treatment stops which means that ensuring compliance is even more important if potential benefits are to be sustained.

Download PDF sample

Rated 4.13 of 5 – based on 3 votes