Do not swallow the cream. If you accidentally swallow any cream, it is unlikely to cause any ill effects but consult your doctor ifyou are concerned.

Summary of Product Characteristics: Zovirax Cold Sore cream. GlaxoSmithKline Consumer Healthcare. Revised March 2014. Treatment should be continued for at least 4 days.If the infection has not healed after this time,treatment can be continued for up to 5 days more.Exfoliate healthy lips. [12] X Research source While it’s not recommended that you irritate sore or chapped lips, exfoliating healthy lips is an important part of your skincare routine. [13] X Expert Source Tymia Yvette In internationally accepted standard tests the systemic administration of Aciclovir did not produce embryotoxic or teratogenic effects in rabbits, rats or mice. Lipsore 5% w/w cream contains cetyl alcohol and propylene glycol which may cause local skin reactions (skin irritation and redness). Aciclovir is predominantly eliminated via the kidneys, primarily by glomerular filtration and to a lesser extent by tubular secretion.

In vitro and in vivo studies of aciclovir cream and aciclovir ointment versus oral aciclovir were carried out to determine the bioavailability of aciclovir in human skin. The in vitro studies used human skin biopsates, whilst the bioassays either used human skin grafts on mice or were carried out in the human eye (3 patients). People who suffer from cold sores can often tellwhen they are about to get a cold sore by a tinglingor itching sensation. Lipsore 5% w/w Creamshould be used at this tingling stage or just afterskin bl isters appear. Advise patients to wash their hand before and after applying the cream, and to avoid unnecessary rubbing of the lesions or touching them with a towel, to avoid aggravating or transferring the infection. Side Effects The following convention has been used for the classification of undesirable effects in terms of frequency:-On the basis of continuous absorption the concentration increased as a function of time (higher drug concentrations being found 48 hours post-topical dose than 24 hours post-topical dose). Thus short dosing intervals appear rational for the special treatment of herpes simplex virus (HSV) infections. If you have any further questions on the use of Lipsore 5% w/w Cream askyour doctor or pharmacist. 4. Possible side Effects If you accidentally get cream in your eye, wash out thoroughly with warm water. Consult your doctor if you are concerned. Aciclovir works by preventing the virus from multiplying and spreading so helping the immune system to fight it off. This means it will help the healing process of current sores and prevent new ones from developing. Aciclovir will not eliminate the herpes simplex virus or prevent future outbreaks of cold sores occurring. It also won’t stop you spreading the virus to others. Key features

Moisturize your lips with a hydrating lip balm immediately after exfoliating. [15] X Expert Source Tymia YvetteThe required dose of Lipsore 5% IV should be administered by slow intravenous infusion over a one-hour period.